On September 21, the following notable historical events related to Missouri occurred:
- 1806: The Lewis and Clark Expedition was in the St. Louis area on or around September 21, nearing the completion of their exploration of the Louisiana Purchase, with St. Louis as their final destination, reinforcing Missouri’s role as a central hub.
- 1857: During the prelude to the Civil War, tensions over slavery were high. On or around September 21, pro-slavery groups in St. Louis held meetings to counter abolitionist activities, reflecting Missouri’s divided stance in the national debate.
- 1861: During the Civil War, the aftermath of the First Battle of Lexington (September 20) was unfolding in Missouri. On September 21, Confederate forces under Sterling Price consolidated their victory in Lexington, strengthening their position in the state.
- 1883: The St. Louis-based Anheuser-Busch brewery began expanding its refrigerated shipping operations around September 21, enabling broader distribution of Budweiser and reinforcing Missouri’s prominence in the brewing industry.
- 1930: The Kansas City Stockyards processed a record number of livestock around September 21, underscoring Kansas City’s role as a major agricultural hub and boosting Missouri’s economy.
- 2004: The St. Louis Cardinals played a significant game against the Milwaukee Brewers at Busch Stadium on September 21, with Albert Pujols hitting a key home run, contributing to their strong season and Missouri’s baseball legacy.