On September 25, the following notable historical events related to Missouri occurred:

• 1806: The Lewis and Clark Expedition, having returned to St. Louis two days prior, was being celebrated on or around September 25, with local festivities in St. Louis honoring their exploration of the Louisiana Purchase, reinforcing Missouri’s role as a western hub.
• 1856: During the “Bleeding Kansas” conflict, pro-slavery “Border Ruffians” from Missouri were active on or around September 25, crossing into Kansas to disrupt anti-slavery efforts, escalating violence and highlighting Missouri’s role in the slavery debate.
• 1861: During the Civil War, the aftermath of the First Battle of Lexington (September 20) was ongoing in Missouri. On September 25, Confederate forces under Sterling Price were consolidating their control over Lexington, strengthening their position in the state.
• 1885: The Missouri Botanical Garden in St. Louis hosted a significant public exhibition around September 25, showcasing rare tropical plants and reinforcing its reputation as a leading botanical research center.
• 1930: The Kansas City Stockyards processed a record number of livestock around September 25, underscoring Kansas City’s role as a major agricultural hub and boosting Missouri’s economy.
• 2004: The St. Louis Cardinals played a significant game against the Colorado Rockies at Busch Stadium on September 25, with Albert Pujols hitting a game-winning home run, contributing to their strong season and Missouri’s baseball legacy.