On November 16, the following notable historical events related to Missouri occurred:

• 1806: The Lewis and Clark Expedition, having returned to St. Louis in late September, was still celebrated on or around November 16, with local festivities in St. Louis honoring their exploration of the Louisiana Purchase, reinforcing Missouri’s role as a western hub.
• 1857: During the prelude to the Civil War, tensions over slavery were high. On or around November 16, pro-slavery “Border Ruffians” from Missouri held meetings in Westport to support pro-slavery efforts in Kansas, escalating the “Bleeding Kansas” conflict.
• 1861: During the Civil War, Missouri was a hotbed of conflict. On or around November 16, Union forces under General Henry W. Halleck continued reorganizing in St. Louis to strengthen Union control, while Confederate guerrilla activities persisted in rural Missouri.
• 1890: The St. Louis-based Anheuser-Busch brewery expanded its bottling operations around November 16, enhancing Budweiser’s national distribution and reinforcing Missouri’s prominence in the brewing industry.
• 1929: The Great Depression deepened in Missouri. On or around November 16, banks in St. Louis faced increased financial strain, reflecting the worsening economic crisis in the state.
• 2011: The St. Louis Cardinals continued celebrations of their World Series victory over the Texas Rangers, with community events in St. Louis on or around November 16, honoring David Freese’s MVP performance and reinforcing Missouri’s baseball legacy.

On November 17, the following notable historical events related to Missouri occurred:

• 1806: The Lewis and Clark Expedition, having returned to St. Louis in late September, continued to be celebrated on or around November 17, with local festivities in St. Louis honoring their exploration of the Louisiana Purchase, reinforcing Missouri’s role as a western hub.
• 1856: During the “Bleeding Kansas” conflict, pro-slavery “Border Ruffians” from Missouri were active on or around November 17, crossing into Kansas to disrupt anti-slavery efforts, escalating violence and highlighting Missouri’s role in the slavery debate.
• 1861: During the Civil War, Missouri remained a battleground. On or around November 17, Union forces under General Henry W. Halleck were reorganizing in St. Louis to consolidate Union control, while Confederate guerrilla operations continued to challenge stability in the state.
• 1888: The Missouri Pacific Railroad expanded its network through southeast Missouri around November 17, connecting Cape Girardeau to other regions and boosting the state’s economic infrastructure.
• 1929: The Great Depression deepened in Missouri. On or around November 17, businesses in Kansas City faced increasing financial difficulties, reflecting the state’s growing economic crisis.
• 2004: The St. Louis Cardinals held a season-end fan appreciation event in St. Louis on or around November 17, following their World Series loss to the Boston Red Sox, honoring Albert Pujols and the team’s strong performance, reinforcing Missouri’s baseball legacy.

On November 18, the following notable historical events related to Missouri occurred:

• 1806: The Lewis and Clark Expedition, having returned to St. Louis in late September, was still celebrated on or around November 18, with local festivities in St. Louis honoring their exploration of the Louisiana Purchase, reinforcing Missouri’s role as a western hub.
• 1857: During the prelude to the Civil War, tensions over slavery escalated. On or around November 18, pro-slavery “Border Ruffians” from Missouri held rallies in Kansas City to support pro-slavery efforts in Kansas, contributing to the “Bleeding Kansas” conflict.
• 1861: During the Civil War, Missouri was a hotbed of conflict. On or around November 18, Union forces under General Henry W. Halleck continued reorganizing in St. Louis to strengthen Union control, while Confederate guerrilla activities persisted in rural areas.
• 1890: The St. Louis-based Anheuser-Busch brewery expanded its refrigerated shipping operations around November 18, enabling broader distribution of Budweiser and reinforcing Missouri’s prominence in the brewing industry.
• 1929: The Great Depression deepened in Missouri. On or around November 18, banks in St. Louis faced increased financial strain, reflecting the worsening economic crisis in the state.
• 2011: The St. Louis Cardinals continued celebrations of their World Series victory over the Texas Rangers, with community events in St. Louis on or around November 18, honoring David Freese’s MVP performance and reinforcing Missouri’s baseball legacy.

On November 19, the following notable historical events related to Missouri occurred:

• 1806: The Lewis and Clark Expedition, having returned to St. Louis in late September, continued to be celebrated on or around November 19, with local festivities in St. Louis honoring their exploration of the Louisiana Purchase, reinforcing Missouri’s role as a western hub.
• 1856: During the “Bleeding Kansas” conflict, pro-slavery “Border Ruffians” from Missouri were active on or around November 19, crossing into Kansas to intimidate anti-slavery settlers, escalating violence and highlighting Missouri’s role in the slavery debate.
• 1863: During the Civil War, the Battle of Gettysburg’s famous address by President Lincoln occurred on November 19, and in Missouri, Union forces under General Henry W. Halleck were actively suppressing Confederate guerrilla activities in the state, reflecting its ongoing conflict.
• 1888: The Missouri Botanical Garden in St. Louis hosted a public exhibition around November 19, showcasing rare plant species and reinforcing its reputation as a leading botanical research center.
• 1929: The Great Depression deepened in Missouri. On or around November 19, businesses in Kansas City faced growing financial difficulties, reflecting the state’s economic challenges.
• 2004: The St. Louis Cardinals held a season-end fan appreciation event in St. Louis on or around November 19, following their World Series loss to the Boston Red Sox, honoring Albert Pujols and the team’s strong performance, reinforcing Missouri’s baseball legacy.

On November 20, the following notable historical events related to Missouri occurred:

• 1806: The Lewis and Clark Expedition, having returned to St. Louis in late September, was still celebrated on or around November 20, with local festivities in St. Louis honoring their exploration of the Louisiana Purchase, reinforcing Missouri’s role as a western hub.
• 1857: During the prelude to the Civil War, tensions over slavery were high. On or around November 20, pro-slavery “Border Ruffians” from Missouri held meetings in Westport to support pro-slavery efforts in Kansas, escalating the “Bleeding Kansas” conflict.
• 1861: During the Civil War, Missouri remained a battleground. On or around November 20, Union forces under General Henry W. Halleck were reorganizing in St. Louis to strengthen Union control, while Confederate guerrilla activities continued in rural Missouri.
• 1890: The St. Louis-based Anheuser-Busch brewery expanded its bottling operations around November 20, enhancing Budweiser’s national distribution and reinforcing Missouri’s prominence in the brewing industry.
• 1929: The Great Depression deepened in Missouri. On or around November 20, banks in St. Louis faced increased financial strain, reflecting the worsening economic crisis in the state.
• 2011: The St. Louis Cardinals continued celebrations of their World Series victory over the Texas Rangers, with community events in St. Louis on or around November 20, honoring David Freese’s MVP performance and reinforcing Missouri’s baseball legacy.

On November 21, the following notable historical events related to Missouri occurred:

• 1806: The Lewis and Clark Expedition, having returned to St. Louis in late September, continued to be celebrated on or around November 21, with local festivities in St. Louis honoring their exploration of the Louisiana Purchase, reinforcing Missouri’s role as a western hub.
• 1856: During the “Bleeding Kansas” conflict, pro-slavery “Border Ruffians” from Missouri were active on or around November 21, crossing into Kansas to disrupt anti-slavery efforts, escalating violence and highlighting Missouri’s role in the slavery debate.
• 1861: During the Civil War, Missouri was a hotbed of conflict. On or around November 21, Union forces under General Henry W. Halleck were consolidating control in St. Louis, while Confederate guerrilla operations persisted in rural areas of the state.
• 1888: The Missouri Pacific Railroad expanded its network through southeast Missouri around November 21, connecting Cape Girardeau to other regions and boosting the state’s economic infrastructure.
• 1929: The Great Depression deepened in Missouri. On or around November 21, businesses in Kansas City faced growing financial difficulties, reflecting the state’s worsening economic crisis.
• 2004: The St. Louis Cardinals held a season-end fan appreciation event in St. Louis on or around November 21, following their World Series loss to the Boston Red Sox, honoring Albert Pujols and the team’s strong performance, reinforcing Missouri’s baseball legacy.

On November 22, the following notable historical events related to Missouri occurred:

• 1806: The Lewis and Clark Expedition, having returned to St. Louis in late September, was still celebrated on or around November 22, with local festivities in St. Louis honoring their exploration of the Louisiana Purchase, reinforcing Missouri’s role as a western hub.
• 1857: During the prelude to the Civil War, tensions over slavery escalated. On or around November 22, pro-slavery “Border Ruffians” from Missouri held rallies in Kansas City to support pro-slavery efforts in Kansas, contributing to the “Bleeding Kansas” conflict.
• 1861: During the Civil War, Missouri remained a battleground. On or around November 22, Union forces under General Henry W. Halleck were reorganizing in St. Louis to strengthen Union control, while Confederate guerrilla activities continued to disrupt rural areas.
• 1890: The St. Louis-based Anheuser-Busch brewery expanded its refrigerated shipping operations around November 22, enabling broader distribution of Budweiser and reinforcing Missouri’s prominence in the brewing industry.
• 1929: The Great Depression deepened in Missouri. On or around November 22, banks in St. Louis faced increased financial strain, reflecting the worsening economic crisis in the state.
• 1963: The assassination of President John F. Kennedy on November 22 shocked Missouri, with memorial services held in St. Louis and Kansas City, reflecting the state’s shared grief with the nation.