On September 27, the following notable historical events related to Missouri occurred:

• 1806: The Lewis and Clark Expedition, having returned to St. Louis a few days prior, was still being celebrated on or around September 27, with local events in St. Louis honoring their exploration of the Louisiana Purchase, reinforcing Missouri’s role as a western hub.
• 1855: During the “Bleeding Kansas” prelude, pro-slavery Missourians, known as “Border Ruffians,” were active on or around September 27, organizing in Westport to influence Kansas Territory politics, escalating tensions in the region.
• 1861: During the Civil War, the aftermath of the First Battle of Lexington (September 20) was ongoing in Missouri. On September 27, Confederate forces under Sterling Price were consolidating their victory in Lexington, strengthening their hold in the state.
• 1888: The St. Louis-based Anheuser-Busch brewery began expanding its refrigerated shipping operations around September 27, enabling broader distribution of Budweiser and reinforcing Missouri’s prominence in the brewing industry.
• 1933: The Great Depression affected Missouri, and on or around September 27, New Deal-funded projects in St. Louis began constructing public infrastructure, providing jobs and economic relief.
• 2004: The St. Louis Cardinals played a significant game against the Colorado Rockies at Busch Stadium on September 27, with Albert Pujols hitting a crucial home run, contributing to their strong season and Missouri’s baseball legacy.